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Gynaecology & Obstetrics Endocrinology in Relation to Reproduction e0a1f6cf

Which is false regarding HCG?

A
It is a glycopeptide
B
Synthesized by cytotrophoblast
C
Doubling time is 2 days
D
High levels are seen in multiple pregnancies
High-Yield Explanation
Ref: Text book of Obstetrics by D. C.Dutta. 7th, ed. Pg. 58Explanation:Human chorionic Gonadotrophin (HCG)HCG is a glycoprotein, it consists of a and b subunits, a subunit of HCG is biochemically similar to LH.FSH and TSH.HCG is synthesized by syncitiotrophoblast.Half life of HCG is 24 hrs and Doubling time is 1.4 to 2 daysHCG is responsible for rescue and maintenance of corpus luteum till 6 wk of pregnancy.Maximum level is reached between 60 to 70 days of pregnancy.High levels of HCG are seen inMultiple pregnancyHydatidifom moleChoriocarcinomaDown's syndrome fetusREMEMBER:Protein hormones produced by placenta are:HCGHuman placental lactogenPAPP-A (pregnancy associated placental protein A)Steroid hormones produced by placenta areEstrogenProgesterone

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