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Physiology General e09641d7

The type of hemoglobin that has least affinity for 2,3- Diphosphoglycerate (2,3-DPG) or (2,3-BPG) is:

A
Hg A.
B
Hg F
C
H B
D
Hg A2.
High-Yield Explanation
B i.e. HgF 2,3. DPG does not combine with fetal hemoglobin 2,3DPG & Hemoglobin 2,3 DPG is present in high concentration in erythrocytes (HbA> HbA2) 2,3 DPG greatly reduces the affinity of Hb to O2 Q (shifts O2-dissociation curve to right) Fetus Hb (HbF) consists of a2Y2, this tetramer has much lower affinity for 2-3 DPG than adult HbQ Corresponding a higher affinity for O2.

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