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Medicine C.N.S. e07e9372

Investigation of choice for myasthenia gravis?

A
Single Fiber E.M.G
B
Muscle biopsy
C
Nerve conduction velocity
D
Anti -acetylcholine receptor antibody
High-Yield Explanation
Ans. (a) Single Fiber E.M.GRef: Harrison 19th ed. / 442e-6* Single fiber E.M.G is the investigation of choice for myasthenia gravis and shows a decremental response* Anti-acetylcholine receptor blocking antibody TITER is the most specific test for diagnosis of myasthenia gravis. Also remember that Tensilon test is a screening test for myasthenia gravis. False positive tensilon test can be seen in motor neuron disease.

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