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Medicine General e0438f23

A patient has normal PT and Platelet Count. The aPTT is increased and factor VIII levels are observed to be 60 lukIL (60%). There is no associated history of bleeding even after a surgical procedure. The most likely diagnosis is:

A
Factor IX deficiency
B
Factor VIII inhibitors
C
Lupus anticoagulant
D
Thalassemia
High-Yield Explanation
Answer is C (Lupus Anticoagulant) Isolated prolongation of aPTT with no clinical history of bleeding suggests the presence of Lupus anticoagulant or deficiency of contact factors (Factor XII, Prekallikrein or HMWK)

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