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Gynaecology & Obstetrics Reproductive physiology and hormones in females e040deb8

Major sources of androgen in females are all except :

A
Adrenals
B
Ovaries
C
Peripheral conversion to androgen precursors in the liver, gastrointestinal tract and adipose tissue
D
Corpus luteum
High-Yield Explanation
Androgen Production in Females Testosterone Androstenedione DHEA DHEA-S Ovary 25% 50% 20% Adrenal Coex 25% 50% 50% 100% Androstenedione 50% DHEA-S 30% 50% of Androstenidione is peripherally conveed to testosterone Testosterone is 80% bound to SHBG and 19% to Albumin, hence only 1% is free and active In Hirsute women 2% free and active In Men 3% free and active Ref: Clinical Gynecologic Endocrinology and Infeility; Eighth Edition; Chapter 13

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