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Pharmacology A.N.S. dffc3849

Mechanism of action of pralidoxime is:

A
Stimulation of ACh receptors
B
Inhibition of breakdown of ACh
C
Blockade of ACh receptors
D
Reactivation of AChE enzyme
High-Yield Explanation
Ans. (D) Reactivation of AChE enzyme(Ref: Katzung 10/e p116; KDT 8th/e p123)Pralidoxime and diacetylmonoxime are cholinesterase regenerator compounds used for organophosphate poisoning.

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