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Pediatrics Genetic and genetic disorders dfe92c5a

Non-invasive prenatal screening (NIPS) is paicularly useful in the modern era of diagnosis in clinical genetics. Which of the following statements is not true regarding this test?

A
Useful in screening for aneuploidies
B
Evaluates maternal blood for abnormalities
C
HIgh positive predictive value
D
Positive test need confirmation by invasive testing
High-Yield Explanation
Non-invasive prenatal screening (NIPS) has a high negative predictive value. NIPS: Useful in screening high-risk pregnancies for aneuploidies Done after 10 weeks of gestation Evaluates maternal blood for screening Positive tests need confirmation by invasive testing (like amniocentesis, Chorionic villous sampling) Ref: Ghai essential pediatrics 9th edition Pgno: 643

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