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Which of the following drugs is most effective against an organism producing aminoglycoside inactivating enzymes?

A

Amikacin

B

Streptomycin

C

Gentamicin

D

Tobramycin

High-Yield Explanation

(Ref: KDT 6/e p724) Amikacin is most resistant to aminoglycoside inactivating enzymes. Aminoglycosides are not effective against anaerobes.

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