Propofol infusion syndrome all Except
High-Yield Explanation
Propofol infusion syndromeA lethal syndrome, associated with infusion of propofol for 48 hours or longerOccurs in children and critically illOccurs as a result of failure of free fatty acid metabolism and failure of the mitochondrial respiratory chain.Features are-cardiomyopathy with acute cardiac failure, metabolic acidosis, skeletal myopathy, hyperkalemia, hepatomegaly and lipemia.(Refer: stoelting's pharmacology and physiology in anaesthetic practice, 5th edition, pg no.160-168)