Full 2L QBank
Medicine Ataxic Disorders decbd81a

Fredrich's ataxia is caused by -

A
Point mutation
B
Expanded trinucleotide repeat
C
Missense mutation
D
Inversion
High-Yield Explanation
Ans. is 'b' i.e., Expanded trinucleotide repeat o Freidrich ataxia is an autosomal recessive disorder.o It is caused by loss of Junctional mutation in frataxin gene (FxN) gene.o Frataxin gene is located on chromosome 9ql3.o Majority of patients have an expanded trinucleotide repeat in intron 1 of both alleles of frataxin gene.

Related Medicine MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now