Center of complement pathway -

- the central process in the complement cascade is the activation of C3. - in classical pathway, activation of C3 is achieved by C4b2a ( classical C3 convease ). - the activation of C3 without prior paicipation of C4b2a is known as alternative pathway. Reference : Anathanarayan & paniker's 9th edition, pg no: 122,123 <\p>