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Biochemistry DNA Replication de8d272b

Unwinding of DNA during replication is done by-

A
Ligase
B
Helicase
C
Polymerase
D
Prinase
High-Yield Explanation
Ans. is 'b' i.e., HelicaseProteins involved in replicationProteinFunctionHelicaseCauses unwinding of DNA using ATPSSB (Single strand binding protein)Keeps two strands seprate, prevents renneiling of two strandsTopisomerase I and IIThey have both nuclease (strand cutting) and ligase activity, hence they relieve torsinal strain that results from helicase induced unwindingDN A pnmaseInitiates synthesis of RNA primerDNA polymeraseDeoxyribonucleotide polymerizationDNA Jigase/nick sealingSeals the single stranded nick between nascent chaind and okazaki fragments

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