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Medicine AML & ALL de7f23cd

Which of the following ALL will not show a dismal prognosis?

A
Age between 1-10 years
B
TLC > 1 lac
C
Petechiae
D
t(9:22)
High-Yield Explanation
Prognostic factor in acute lymphoblastic leukemia Excellent prognosis Excellent prognosis t(12;21) and TEL-AML1 fusion Hyperdiploidy and trisomy of specific chromosomes (4, 10 and 17) is associated with an excellent prognosis. Age > 1 years and < 10 years Dismal prognosis t(9;22) or Philadelphia chromosome and BCR-ABL fusion Hypodiploidy with chromosome number<45 is associated with a poor prognosis Age > 10 years WBC> 50,000/cu.mm3 CNS leukemia at presentation

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