A 6-year-old girl presents with precocious pubey, some bony lesions & hyperpigmented skin lesions as shown below. What is the most probable diagnosis?
High-Yield Explanation
The history & image given in question suggests the diagnosis of MC CUNE ALBRIGHT SYNDROME: MC CUNE ALBRIGHT SYNDROME: - Characterized by Triad of Precocious pubey Cafe au lait spots Polyostotic fibrous dysplasia - Occurs due to somatic activating mutation of stimulatory G- protein - Associated endocrine abnormalities are * Hypehyroidism Rickets GH excess Precocious pubey