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Pharmacology C.N.S de70eb19

A lady suffering from GTCS is on phenytoin. She becomes pregnant. What advice u will give to the patient:

A
Stop phenytoin, start phenobarbitone
B
Stop phenytoin, start lamotrigine
C
Stop phenytoin, start magnesium infusion
D
Continue phenytoin and add folic acid in last 2 weeks of pregnancy along with vitamin k
High-Yield Explanation
Ans. D. Continue phenytoin and add folic acid in last 2 weeks of pregnancy along with vitamin kThough phenytoin is teratogenic drug, but if patient becomes pregnant during the course of the treatment, discontinuation of therapy can precipitate status epilepticus. So we should continue the drug along with folic acid supplementation and vitamin K in 2 and 3 trimesters.

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