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Physiology General de65581d

True regarding myocardial O2 demand?

A
Inversely related to heart rate
B
Has constant relation to external cardiac work
C
Directly proportional to duration of systole
D
Is negligible at rest
High-Yield Explanation
Oxygen demand depends on the work being done. The work done is to pump the blood which is in the ventricles (preload) against the resistance in the aorta (afterload).  So, myocardial oxygen demand depends on Rate - Directly proportional Contractility - Directly proportional Intramyocardial tension - Directly proportional After load - Directly proportional Preload - Directly proportional Wall thickness - Inversely proportional The oxygen demand of myocardium is not having the same change with varying external works.

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