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Pharmacology General de2045fd

The therapeutic effect of sulfasalazine in ulcerative colitis is exerted by :

A
Inhibitory action of the unabsorbed drug on the abnormal colonic flora
B
Breakdown of the drug in colon to release 5–amino-salicylic acid which suppresses inflammation locally
C
Release of sulfapyridine having antibacterial property
D
Systemic immunomodulatory action of the drug
High-Yield Explanation
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