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Pathology General ddf32bc2

Which finding on electron microscopy indicates irreversible cell injury-

A
Dilatation of endoplasmic reticulum
B
Dissociation of ribosomes from rough endoplasmic reticulum
C
Flocculent amorphous densities in the mitochondria
D
Myelin figures
High-Yield Explanation
Ans. is 'c' i.e., Flocculent densities in mitochondria Mechanism of irreversible cell injury :? Membrane damage is the central factor in the pathogensis of irreversible cell injury. Note : o Earliest change of reversible cell injury is cellular swelling. o Myelin figures (laminated structure) derived from damaged membrane of organelles and plasma membrane, first appear during reversible injury, but become more pronounced in irreversible injury.

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