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ENT General dde96930

Diagnostic test for CSF rhinorrhea is ?

A
Beta - 2 microglobulin
B
Beta - 2 transferrin
C
Thyroglobulin
D
Transthyretin
High-Yield Explanation
Ans. is 'b' i.e., Beta-2 transferrin Beta-2 transferrin is a CSF-specific variant of transferrin and is used as an endogenous marker of CSF leakage. Beta-2 transferrin is formed by loss of sialic acid due to the presence of neuraminidase in the central nervous system. Beta-2 transferrin has also been called CSF-specific transferrin and tau protein.

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