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Physiology General dde32905

Neurotransmitter in subthalamic nuclei ?

A
Glutamate
B
GABA
C
Serotonin
D
Ach
High-Yield Explanation
Ans. is 'a' i.e., GlutamateBasal ganglia are richly connected with one another. These connections include :?1) Dopaminergic nigrostriatal projection from the substantia nigra pars compacta (SNPC) to the striatum caudate nucleus and putamen) and corresponding GABAergic projection from striatum to substantia nigra pars reticulata (SNPR). Dopamine is the major neurotransmitter in substantia nigra.2) The striatum has GABAergic projections to both globus pallidus inner segment (IS) as well as globus pallidus external segment (ES).3) Globus pallidus ES has GABAergic projections to subthalamic nucleus and to globus pallidus IS.4) Subthalamic nucleus has Glutamate-ergic projections on both globus pallidus IS as well as globus pallidus ES.5) Cholinergic interneurons are there within the striatum.

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