Full 2L QBank
Medicine General dd8595b0

Mytonic dystrophy is due to-

A
Expansion in coding region
B
CAG triple nucleotide repeat mutation
C
CTG triple nucleotide repeat mutation
D
Involves chromosome 15
High-Yield Explanation
Answer-C. CTG triple nucleotide repeat mutationMyotonic dystrophy is associated with a trinucleotide CTG repeat expansion on chromosome 19.This expansion affects the mRNA for the dystrophila myotonia protein kinase (DMPK).Triple nucleotide repeat mutations Normally, a codon is triplet (trinucleotide) (e.g. for CGG it is 5-50 and CGG triplet codon can be repeated, at a stretch, 5-50 times) Non-coding region

Related Medicine MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now