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Pharmacology Central Nervous system dd374811

Duration of action of flumazenil is

A
5minute
B
10minute
C
20minute
D
30minute
High-Yield Explanation
Duration of action of flumazenil is 30-60min. So the best answer seems to be 30min The onset of action is about 1 to 2 minutes; 80% response is seen within the first 3 minutes. Peak effect is 6 to 10 minutes after administration.Duration range is from 19 minutes to 50 minutes as it depends on the dose was given and benzodiazepine plasma concentrations Ref: Goodman and Gilman 13th ed.

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