AU ER rods seen in -

Ans. is 'b' i.e., M3 AMLAcute myelogenous leukemia (AML)o AML is a cancer of myeloid line of WBCs, characterized by the rapid proliferation of abnormal cells which accumulate in the bone marrow and interfere with the production of normal blood cells,o AML is the most common acute leukemia affecting adults.o The diagnosis of AML is based on finding that myeloid blasts make up more than 20% of the cells in the marrow,o Myeloblasts are myeloperoxidase (peroxidase positive)o Auer rods (represent abnormal azurophilic granule) are also present in myeloblasts and their presence is taken to be definitive evidence of myeloid differentiation.o In some AMLs, blast cells exhibit differentiation of other myeloid stem cell line (other than myeloblast), e.g.,Monoblast - Lack auerrods, peroxidase negative, but nonspecific esterase positive.Megakaryocytic differentiationErythroblast