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Pathology General dcb97307

Karyotyping is useful in diagnosis of -

A
Autosomal recessive disorders
B
X-linked recessive disorders
C
Chromosomal abnormalities
D
Biochemical abnormalities
High-Yield Explanation
Ans. is 'c' i.e., Chromosomal abnormalitieso Karyotyping is the study of chromosomes and is used in cytogenetics to study the chromosomal abnormalities. o After arresting the cells in metaphase the chromosomes are examined to see for:(i) Numbers --> to detect abnormalities in chromosome numbers such as aneuploidy (trisomy, tetrasomy), polyploidy.(ii) Structure ---> to detect structural chromosomal anomalies such as translocations, deletions, inversions.

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