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Pharmacology Pharmacokinetics dc663690

Which of the following is a pro drug is -

A
Levodopa
B
Poiglitazone
C
Dexamethasone
D
Captopril
High-Yield Explanation
Ans. is 'a' i.e., Levodopa Prodrugo Few drugs are inactive as such and need conversion in the body to one or more active metabolites,o Such a drug is called a prodrug.o All the drugs in following table are very important, sorry, I can not shorten the listProdrugLevodopaEnalaprila - MethyldopaChloralhydrateDipiveffineOxcarbazepinePrednisoneBacampicillinSulfasalazineCyc lophospham ideMercaptopurineFluorouracilSulindacAzathioprineCortisoneBenorilateProguanilZidovudinTerfenadineProntosilo Advantages of prodrugs over active formMore stableBetter bioavailabilityLess side effects and toxicity.

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