Biochemistry General dc5d515b Defect in lipoprotein lipase enzyme leads to A Type I hyperlipoproteinemia B Type II a hyperlipoproteinemia C Type II b hyperlipoproteinemia D Type III hyperlipoproteinemia High-Yield Explanation Defect in either lipoprotein lipase or its cofactor Apo C II leads to Type I hyperlipoproteinemia chylomicrons, VLDL gets elevated in the body.