Pediatrics Neoplastic disorders of WBCs dc3d29e4

AML with worst prognosis:

8/21 translocation

Inversion 16

Normal cytogenetics

Monosomy 7

High-Yield Explanation

PROGNOSIS OF AML: Good prognostic factors: t(8;21) inv16 t(15;17) CEBPA mutation NPM mutation Down syndrome Bad prognostic factors: Monosomy 7 5q deletion FLT3 - internal tandom duplication

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