Pharmacology Central Nervous system dc071f0e

Regarding phenytoin, false is:

Induces microsomal enzymes

At very low doses, zero order kinetics occur

Higher the dose, higher is the half life

Highly protein bound

High-Yield Explanation

*Phenytoin follows saturation kinetics (kinetics changes from first order to zero within therapeutic concentration), Zero order kinetics are seen at high doses. *It is also a potent enzyme inducer and can increase the metabolism of various drugs. *It is 80-90% plasma protein bound. REF: KATZUNG 14TH ED.

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