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Pathology General pathology dbf60196

BRCA 1 gene is located on chromosome

A
17p21
B
17q21
C
13p21
D
13q21
High-Yield Explanation
A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which are tumour suppressor genes. ... Women with harmful mutations in either BRCA1 or BRCA2 have a risk of breast cancer that is about five times the normal risk, and a risk of ovarian cancer that is about ten to thiy times normal.

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