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Pediatrics Inborn Errors of Metabolism dbc3c190

Not a feature of Hartnup's disease:

A
Pellagroid skin lesion
B
Cerebellar ataxia
C
Mental retardation
D
Psychological disturbances
High-Yield Explanation
c. Mental retardation(Ref: Nelson's 20/e p 636-642, Ghai 8/e p 653-655)Clinical features of Hartnup disease:Most children with Hartnup defect remain asymptomaticMajor clinical manifestation in symptomatic patient is cutaneous photosensitivity: pellagra-like rash on sun exposureSome patients may have intermittent ataxia & Psychological disturbances, but mental development is usually normal.

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