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Physiology Endocrinology dbb619fc

Insulin secretion is/are increased by all except

A
Glucose
B
Secretin
C
VIP
D
Glucagon
High-Yield Explanation
Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. Insulin causes cells in the liver, skeletal muscles, and fat tissue to absorb glucose from the blood. In the liver and skeletal muscles, glucose is stored as glycogen, and in fat cells (adipocytes) it is stored as triglycerides.Glucose- is the impoant factor for the regulation of insulin secretion.Secretin is a hormone that both controls the environment in the duodenum by regulating secretions of the stomach and pancreas and regulates water homeostasis throughout the body.VIP is vasoactive intestinal polypeptide.glucagon is a polypeptide hormone secreted by the alpha cells of the islets of Langerhans in response to hypoglycemia or to stimulation by growth hormone. It increases blood glucose concentration by stimulating glycogenolysis in the liver and can be administered parenterally to relieve severe hypoglycemia from any cause, especially hyperinsulinism.Ref: Ganong&;s review of medical physiology;24th edition; page no-441

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