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Pharmacology Epilepsy db4eb62a

A 30 year old female epileptic on phenytoin, developed weakness and fatigue. Blood examination revealed Hb = 4.6 gm. MCV = 102 fl and MCH = 40 pg/dl. What is the most probable diagnosis

A
Heart failure
B
Iron deficiency anemia
C
Phenytoin induced agranulocytosis
D
Megalobalstic anemia.
High-Yield Explanation
Ans. is 'd' i.e. Megaloblastic anaemiaNormal valuesMCU- 86 - 98 fLMCH- 28 - 33 pg/cellHb (female) - 12-16 gm/dLLab finding in this pt. go in favour of megaloblastic anemia. H/O phenytoin intake is also suggestive of same.

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