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Pharmacology Central Nervous system daddeef9

True statement about dezocine is:

A
It is slower acting than morphine
B
It is less potent than morphine
C
It acts GABA receptors
D
It doesn't increase histamine release
High-Yield Explanation
Ref: Goodman and Gilman 10/e p602 *Dezocine is slightly more potent and faster acting opioid than morphine with a similar duration of action. It is a paial agonist antagonist opioid. *It is active at u receptors and side effect are similar to those of morphine. *Dezocine doesn't increase plasma histamine and produces less hypotension than morphine or pentazocine. *Dezocine is effective for moderate to severe pain but can cause myocardial depression.

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