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Pathology General daa92887

Which of the following condition is associated with coagulative necrosis?

A
Tuberculosis
B
Sarcoidosis
C
Cryptococcal infection
D
Gangrene
High-Yield Explanation
Coagulation necrosis is seen in TB. Caseous necrosis is so called because of its cheesy white appearance. Microscopically, the necrotic focus appear as amorphous granular debris composed of fragmented, coagulated cells enclosed within an inflammatory border. Necrosis refers to a spectrum of morphologic changes that follow cell death in living tissue, largely resulting from progressive degradation action of enzymes on the lethally injured cells.Types of necrosis are:Coagulative necrosis : seen in myocardial infarctionLiquefactive necrosis: seen in focal bacterial or occasional fungal infectionsCaseous necrosis: seen in TBFat necrosis: seen in acute pancreatitis Ref: Robbins Pathologic Basis of Disease, 6th Edition, Page 16-7

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