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Medicine All India exam da770ee3

Which among the following statements is wrong

A
Light chains are synthesised in slight excess normally in plasma cells
B
Qualitative assessment of M component can be done by electrophoresis
C
M components are detected in chronic myeloid leukaemia
D
In 20% myelomas, only light chains are produced
High-Yield Explanation
Qualitative assessment of M component is done by immune electrophoresis. Electrophoresis is used for quantitative assessment of M component. M component can also be detected in other lymphoid malignancies, CML, Can breast, colon cancer , non neoplastic condition like cirrhosis, sarcoidosis, rheumatoid ahritis, myasthenia gravis. Ref : Harrison's Principles of Internal Medicine, 21st Edition, p 710-712.

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