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Anatomy General anatomy d9d51e30

Which of the following criteria can be used to determine if a pheochromocytoma lesion is benign or malignant

A
Blood vessel invasion
B
Cannot be determined by microscopic examination
C
Hemorrhagic and necrosis
D
Nuclear pleomorphism
High-Yield Explanation
Ref Robbins 8/e p1159-1161;9/e p1135 Pheochromocytoma and their related counterpas in extra adrenal sites called paraganglioma, are notorious Because the only reliable indicator of metastasis potential is the presence of distant metastasis . Very malignant appearing tumors may not metastasize and benign appearing tumors may produces metastases . These tumors should all be considered " potentially malignant" .

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