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Pharmacology Central Nervous system d9882e46

A person consumes large quantities of alcohol daily since 20 years.He is physically dependent on alcohol. Drug should be given to this person is:

A
Disulfiram
B
Acamprosate
C
Naltrexone
D
Chlordiazepoxide
High-Yield Explanation
Disulfiram is the main drug tahtbsi used to make alcohol consumption an unpleasant experience. Disulfiram inhibit aldehyde dehydrogenase , alcohol is not metabolized and acetaldehyde accumulates which produces unpleasant symptoms and patient develops an aversion.All the other given drugs can be used but primarily displaces is tried. Ref: KD Tripathi 8th ed.

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