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Orthopaedics Tumors d9604b32

All of the following statements about synol cell sarcoma, are true, except -

A
Originate from synol lining
B
Occur more often at extraaicular sites
C
Usually seen in patients less than 50 years of age
D
Knee and foot are common sites involved
High-Yield Explanation
SYNOL SARCOMA Synol sarcoma is so named because it was once believed to recapitulate synovium, but the cell of origin is still unclear. In addition, although the term synol sarcoma implies an origin from the joint linings, less than 10% are intra-aicular. Synol sarcomas account for approximately 10% of all soft tissue sarcomas and rank as the fouh most common sarcoma. MORPHOLOGY. The histologic hallmark of synol sarcoma is the biphasic morphology of the tumor cells (i.e., epithelial-like and spindle cells). Immunohistochemistiy is helpful in identifying these tumors, since the epithelioid and spindle cell poions yield positive reactions for keratin and epithelial membrane antigen, differentiating these tumors from mos other sarcomas. ref : maheswari 9th ed

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