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Medicine Haematology d96026ce

1722. A patient presents with macroglossia and atrophy of tongue papilla. His Hb Is 11.5 and MCV is 100. What should be the next step in Investigating this patient ?

A
B12 estimation
B
Brush biopsy of the lesion
C
Fluconazole treatment
D
Incision biopsy
High-Yield Explanation
<p>Deficiency of vit B12 & folate presents with anemia(macrocytic megaloblastic anemia), glossitis(smooth,beefy,red tongue).Hb level will be below normal range & MCV wil be elevated.So this is a case of vit B 12 deficiency & next choice of investigation is serum Vit B12 assay. </p><p>Harsh mohan textbook of pathology sixth edition pg no 306</p>

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