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Pharmacology General d95ad1e7

Which of the following drugs required a dose adjustment in patient during radiotherapy in order to present radiation toxicity ?

A
Vincristine
B
Dactinomycin
C
Cyclophosphamide
D
6-Mercaptopurine
High-Yield Explanation
Ans. is 'b' i.e., Dactinomycin o Like anthracyclines (doxo and daunorubicin), dactinomycin can also cause radiation recall syndrome and the dose should be adjusted with radiotherapy.

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