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Biochemistry General d93a5a85

1" carbon of pentose sugar of nucleic acid joins -

A
N-9 of pyrimidine
B
N-1 of pyrimidine
C
N-1 of purine
D
None of the above
High-Yield Explanation
Ans. is 'b' i.e., N-1 of pyrimidinePenose sugars Pentose sugar present in DNAs is deoxyribose and in RNAs it is ribose. A pentose sugar (ribose or deoxyribose) is linked to a nitrogenous base (purine or pyrimidine) covalent N-glycosidic bond to form nucleoside.This linkage joins the Carbon-1 ofpentose sugar with nitrogen-9 of the purine base or nitrogen-I of pyrimidine base.Nucleoside is linked to phosphoric acid to form nucleotide.For example, purine base 'adenine' combines with ribose sugar to form adenosine, a nucleoside (ribonucleoside). o This, adenosine (nucleoside) combines with phosphate group to form adenosine monophosphate : AMP, a nucleotide (ribonucleotide).If the pentose sugar is deoxyribose (instead of ribose) the resulting nucleotide is deoxyribonucleotide.Adenine + Ribose Adenosine (ribonucleoside 4 AMP (ribonucleotide)Phosphate groupAdenine + Deoxyribose Deoxyadenosine (Deoxynucleoside) 4 dAMP (deoxyribonucleotide) Phosphate group

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