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Gynaecology & Obstetrics General d9137c27

A pregnant mother is treated with oral anticoagulant.The likely congenital malformation that may result in the fetus is:

A
Long bones limb defect
B
Cranial malformation
C
Cardiovascular malformation
D
Chondrodysplasia Punctata
High-Yield Explanation
Warfarin is an anticoagulant drug. Action : Interferes with the synthesis of the vitamin K dependent factors like II, VII, IX and X. Side effects: Hemorrhage It leads to: – Contradi’s syndrome : skeletal and facial anomalies in the fetus – Chondrodysplasia punctata in the fetus. Miscarriage, IUGR and stillbirths accentuates neonatal hypothrombinemia.

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