All of the following statements about carcinoid syndrome are true except:

Answer is C (Metastasis to bone is common in Midgut Carcinoids): Palliative Care (Oxford University Press, 2009)/ 452; Multiple references Metastasis to bone is rare in Midgut Carcinoids and is Common in Foregut Carcinoids. Features Foregut Midgut Hindgut Site Esophagus Jejunum Transverse Colon(Distal) Stomach Ileum Descending Colon Duodenum (Proximal) Appendix Rectum Liver; Gallbladder Meckel's Diveiculum Pancreas Ascending Colon Respiratory tract Transverse Colon (Proximal) Argentaffin Stain Negative Positive +/? Carcinoid Syndrome Atypical Typical Syndrome is Rare (Prolonged purple flush; (Sho pink red flushes; Headache; , lacrimation; Diarrhoea; Wheezing; Bronchoconstriction) Dyspnea; Cardiac Fibrosis; Pallegra) Metastasis to Bone Common Rare Common Plasma Serotonin Normal Elevated +/? Typical Urinary 5-HTP 5-HIAA, 5HT Rarely 5HT Metabolite