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Biochemistry General d8bf8ae1

Not gluconeogenic?

A
Acetyl CoA
B
Lactate
C
Glycerol
D
Alanine
High-Yield Explanation
Ans. is 'a' i.e., Acetyl CoA Substrates for gluconeogenesis are lactate (lactic acid), pyruvate, glycerol, glucogenic amino acids (all amino acids except leucine and lycine), propionate and intermediates of citric acid cycle.Acetyl CoA canot be conveed into glucose. This is because the reactionPyruvate Acetyl-CoA" is irreversible.Pyruvate carboxylasePyruvate is the staing substrate for gluconeogenesis (Pyravate_ Oxaloacetate). As acetyl CoA cannot be conveed into pyruvate, it is not a substrate for gluconeogenesis.

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