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Pediatrics General d89b4235

All of the following conditions are observed in Marasmus, except -

A
Hepatomegaly
B
Muscle wasting
C
Low insulin levels
D
Extreme weakness
High-Yield Explanation
Ans. is 'a' i.e., Hepatomegaly Changes in body composition in P.E.M. o Fluid considerations? Total body water in malnourished children is increased to 70-80% of body weight as compared to 60% in age matched well noarished controls. Activity of the sodium pump* is reduced. o Metabolic alterations. B.M.R. is reduced by 30% and energy expenditure due to inactivity is very low Child may behave like poikilotherm. o Endocrine changes. Insulin levels are reduced (child has glucose intolerance) Coisol and growth hormone levels are increased. o Cardiovascular system Cardiac output and stroke volume are reduced Blood pressure is low and renal perfusion is compromised. o Renal function Glomerular.filtration rate and renal plasma flow are reduced in severe P.E.M. Urinary phosphate and sodium excretion are reduced.

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