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Medicine Oncology d88b81dd

AFP is marker for?

A
Hepatoma
B
Seminoma
C
Neural tube defects
D
All of the above
High-Yield Explanation
Ans. D. All of the above. (Ref. H - 17th / pg. 483)# AFP is tumor marker for: Hepatoma# Raised maternal AFP is a marker for: Neural tube defectsTumor MarkersCancerNon-Neoplastic ConditionsHormonesHuman chorionic gonadotropinGestational trophoblastic disease, gonadal germ cell tumorPregnancyCalcitoninMedullary cancer of the thyroid CatecholaminesPheochromocytoma Oncofetal AntigensAlphafetoproteinHepatocellular carcinoma, gonadal germ cell tumorCirrhosis, hepatitisCarcinoembryonic antigenAdenocarcinomas of the colon, pancreas, lung, breast, ovaryPancreatitis, hepatitis, inflammatory bowel disease, smokingEnzymesProstatic acid phosphataseProstate cancerProstatitis, prostatic hypertrophyNeuron-specific enolaseSmall cell cancer of the lung,neuroblastoma Lactate dehydrogenaseLymphoma, Ewing's sarcomaHepatitis, hemolytic anemia, many othersTumor-Associated ProteinsProstate-specific antigenProstate cancerProstatitis, prostatic hypertrophyMonoclonal immunoglobulinMyelomaInfection, MGUSoCA-125Ovarian cancer, some lymphomasMenstruation, peritonitis, pregnancyCA 19-9Colon, pancreatic, breast cancerPancreatitis, ulcerative colitisCD30Hodgkin's disease, anaplastic large cell lymphoma-CD25Hairy cell leukemia, adult T cell leukemia/lymphoma-AFP, gamma-GTP, hepatoma specific gamma-GTP, P-III-P, PIVKA-II and 5'-NPD-V are sensitive and useful markers for diagnosis of hepatoma.Carcinoid tumors immunocytochemically can contain numerous GI peptides: gastrin, insulin, somatostatin, motilin, neurotensin, tachykinins (substance K, substance P, neuropeptide K), glucagon, gastrin-releasing peptide, VIP, PP, other biologically active peptides (ACTH, calcitonin, growth hormone), prostaglandins, and bioactive amines (serotonin).CA 19-9 and CEA for gallbladder-biliary tract cancer and pancreas cancer, and DUPAN-2 and POA for pancreas cancer.

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