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Medicine Endocrinology d83856ca

What is the most likely underlying diagnosis in this 82-year-old patient with diabetes mellitus who had undergone a total hip replacement 10 years previously?

A
Colon cancer
B
Hypogammaglobulinemia
C
Hypophosphatasia
D
Osteosarcoma
High-Yield Explanation
Answer A. Colon cancerThere is free air extending lateral to the greater trochanter. Intra-articular cultures grew Clostridium septicum, which has a known association with colorectal cancer. Subsequent colonoscopy revealed a fungating colonic adenocarcinoma.

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