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Pharmacology A.N.S. d806af03

Which of the following sympathetic receptors acts as vasoconstriction and vasodilatation:

A
Alpha 1 and Alpha 2
B
Alpha 1 and Beta 1
C
Alpha 1 and Beta 2
D
Beta 1 and Beta 2
High-Yield Explanation
(Ref: Katzung 14th ed. pg. 145-47)Alpha 1 and Beta 2 receptors present at blood vessels causing vasoconstriction and vasodilatation respectively.Sympathetic receptors, their location, function and G protein.ReceptorLocationFunctionG-Proteina1BV, smooth muscle, Salivary glandsVasoconstriction Increase secretionGqa2Presynapse Beta pancreatic cellBrake/Inhibit NA releaseDecrease insulin releaseGib1Heart JG cellInc Heart rate Renin releaseGsb2LungsSmooth muscle LiverBronchodilatation Relaxation of smooth muscles GlycogenolysisGsb3Adipocyte Detrusor muscleLipolysis, thermogenesis Bladder relaxGs

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