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Anatomy G.I.T d7fecf26

False about PSC

A
PSC in UC, the association is 30%
B
Low incidence of cholangitis
C
Increased incidence of colonic carcinoma in PSC+UC
D
Despite the presence of diffuse disease, hepatic duct bifurcation is most severely structured segment
High-Yield Explanation
Primary sclerosing cholangitis PSC is a cholestatic liver disease characterized by fibrotic strictures involving intrahepatic and extrahepatic biliary tree in the absence of a known precipitating cause More common in HLA B8/DR3 Incidence of UC in PSC ranges from 75-80% PSC is present in 5.5% of patients with chronic UC Ref: Sabiston 20th edition Pgno :1508-1509

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