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Pharmacology Endocrinology d7efb9c5

Drug given for acute gout:

A
Aspirin
B
Indomethacin
C
Febuxostat
D
Allopurinol
High-Yield Explanation
Ref: Katzung, 14th ed. pg. 648* Primary gout is seen due to decreased uric acid excretion* Secondary gout can be secondary to any cause causing hyperuricemia.* DOC for acute gout: NSAID-DOC (Indomethacin), Colchicine and corticosteroids# Colchicine is fastest acting. It is NOT an anti-inflammatory drug but it specifically suppresses gout inflammation.# Not preferred over NSAID because of its side effects of GI upset.* All NSAIDS can be given in acute gout EXCEPT aspirin as it competes with tubular excretion of uric acid leading to Hyperuricemia.* Probenecid: Has uricosuric action* DOC for chronic gout: Allopurinol

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